Weight problems drug brings coronary heart well being profit alongside weight reduction, research says
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DUBLIN — Taking Novo Nordisk’s new weight problems drug could assist scale back the chance of coronary heart illness in addition to boosting weight reduction, in response to new analysis from the US.
After a yr of taking semaglutide, marketed as Wegovy, sufferers’ danger of affected by circumstances like a coronary heart assault or a stroke over the following ten years dropped to six.3% from 7.6% when measured by a generally used calculator, researchers on the Mayo Clinic discovered.
The outcomes, which had been offered this week on the European Congress on Weight problems in Dublin, are among the many first indication that the burden loss induced by the brand new GLP-1 agonist medicine like Wegovy additionally brings coronary heart well being advantages — one thing scientists anticipated, however don’t but have a lot complete knowledge to show.
The research was solely carried out amongst 93 sufferers, and the researchers mentioned that extra and bigger research had been wanted to see if the chance discount rating really meant much less sickness and dying long-term.
Novo is predicted to launch outcomes from its five-year SELECT trial wanting into the well being affect of its injectable drug, significantly round coronary heart illness, later this yr. Traders, governments and insurers alike are keenly watching the info.
“This can be very necessary, as a result of we all know weight problems is a danger issue for heart problems,” Dr. Andres Acosta, one of many researchers, instructed Reuters.
“So the query is, with drugs which might be 15% (common weight reduction), can we actually begin enhancing cardiovascular danger and say persons are dying much less?” he mentioned.
The danger was calculated utilizing the American School of Cardiology’s calculator, primarily based on knowledge together with blood stress and levels of cholesterol. The staff assessed the chance earlier than the sufferers — primarily white girls, with a imply BMI of 39.8, however no historical past of coronary heart illness — began the drug in addition to after one yr of taking it.
The analysis was peer reviewed by the congress organizers, the European Affiliation for the Research of Weight problems, however the full paper shouldn’t be but out there. The research was not funded by Novo.
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