Investigational drug might enhance stem cell transplantation for a number of myeloma sufferers – Washington College College of Drugs in St. Louis

Investigational drug might enhance stem cell transplantation for a number of myeloma sufferers – Washington College College of Drugs in St. Louis

Printed within the journal Nature Drugs:

Crees ZD, Rettig MP, Jayasinghe R, Stockerl-Goldstein Okay, Larson S, Arpad I, Milone GA, Martino M, Stiff P, Sborov D, Pereira D, Micallef I, Moreno-Jiménez G, Mikala G, Paciello Coronel ML, Holtick U, Hiemenz J, Qazilbash MH, Hardy N, Latif T, García-Cadenas I, Vainstein-Haras A, Sorani E, Gliko-Kabir I, Goldstein I, Ickowicz D, Shemesh-Darvish L, Kadosh S, Gao F, Schroeder M, Vij R, DiPersio JF. A randomized, placebo-controlled, part III trial evaluating motixafortide and G-CSF to mobilize hematopoietic stem cells for autologous transplantation in a number of myeloma — the Genesis trial. Nature Drugs. April 17, 2023.

This work was supported by the Nationwide Institutes of Well being (NIH), grant numbers R35 CA210084 and R50 CA211466; and BioLineRx Ltd., which makes motixafortide.

Printed within the journal Most cancers Analysis:

Yao L, Wang JT, Jayasinghe RG, O’Neal J, Tsai C, Rettig MP, Tune Y, Liu R, Zhao Y, Ibrahim OM, Fiala MA, Fortier JM, Chen S, Gehrs L, Martins Rodrigues F, Wendl MC, Kohnen D, Shinkle A, Cao S, Foltz SM, Zhou DC, Storrs E, Wyczalkowski MA, Mani S, Goldsmith SR, Zhu Y, Hamilton M, Liu T, Chen F, Vij R, Ding L, DiPersio JF. Single-cell discovery and multi-omic characterization of therapeutic targets in a number of myeloma. Most cancers Analysis. Feb. 13, 2023.

This work was supported by the Paula C. and Rodger O. Riney Blood Most cancers Analysis Fund and the Nationwide Most cancers Institute (NCI) of the Nationwide Institutes of Well being (NIH), grant numbers U24CA211006, U2CCA233303, PJ000021702, R35 CA210084 and R50CA211466.

About Washington College College of Drugs

WashU Medicine is a worldwide chief in tutorial drugs, together with biomedical analysis, affected person care and academic applications with 2,800 school. Its Nationwide Institutes of Well being (NIH) analysis funding portfolio is the third largest amongst U.S. medical faculties, has grown 52% within the final six years, and, along with institutional funding, WashU Drugs commits nicely over $1 billion yearly to fundamental and scientific analysis innovation and coaching. Its school follow is persistently inside the prime 5 within the nation, with greater than 1,800 school physicians working towards at 65 places and who’re additionally the medical staffs of Barnes-Jewish and St. Louis Children’s hospitals of BJC HealthCare. WashU Drugs has a storied historical past in MD/PhD coaching, not too long ago devoted $100 million to scholarships and curriculum renewal for its medical college students, and is residence to top-notch coaching applications in each medical subspecialty in addition to bodily remedy, occupational remedy, and audiology and communications sciences.

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